The Prostaglandin D2 Receptor CRTH2 Contributes to Airway Hyperresponsiveness during Airway Inflammation Induced by Sensitization without an Adjuvant in Mice.

Satoshi HanzawaMakiko SugiuraSusumu NakaeMasahiro MasuoHideaki MoritaKenji MatsumotoKazuyoshi TakedaKo OkumuraMasataka NakamuraTatsukuni OhnoYasunari Miyazaki

Published in: International archives of allergy and immunology (2024)

CRTH2 is responsible for the development of asthma responses in a mouse model of airway inflammation that features prominent involvement of both IgE and mast cells.

Keyphrases

mouse model
chronic obstructive pulmonary disease
early stage
lung function
high fat diet induced
allergic rhinitis
type diabetes
binding protein
wild type
skeletal muscle