Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesion.

Camilla SchinnerBernd M ErberSunil YeruvaJens Waschke

Published in: Acta physiologica (Oxford, England) (2019)

These data demonstrate the interplay of GJs, desmosomes and the β1-adrenergic receptor with regulation of their function by cell cohesion, adrenergic and PKC signalling or SERCA inhibition. These results support the identification of new targets to treat arrhythmogenic cardiomyopathy.

Keyphrases

single cell
heart failure
left ventricular
cell therapy
single molecule
electronic health record
biofilm formation
pseudomonas aeruginosa
protein kinase
deep learning
bioinformatics analysis