Postpartum haemorrhage in high-resource settings: Variations in clinical management and future research directions based on a comparative study of national guidelines.
Pauline L M de VriesC Deneux-TharauxDavid BaudK K ChenSerena DonatiF GoffinetMarian KnightR D'SouzahM SuetersT van den AkkerPublished in: BJOG : an international journal of obstetrics and gynaecology (2023)
Definitions of (severe) PPH varied as to the applied cut-off of blood loss and incorporation of clinical parameters. Dose and mode of administration of prophylactic uterotonics and methods of blood loss measurement were heterogeneous. Recommendations on second-line uterotonics differed as to type and dose. Obstetric management diverged particularly regarding procedures for uterine atony. Recommendations on transfusion approaches varied with different thresholds for blood transfusion and supplementation of haemostatic agents. Quality of guidelines varied considerably.