Activation of CRF1 receptors expressed in brainstem autonomic nuclei stimulates colonic enteric neurons and secreto-motor function in male rats.
Pu-Qing YuanS Vincent WuAndreas StengelKen SatoYvette TachéPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2021)
CRF1a and its splice variants are expressed in brainstem nuclei, and activation of CRF1 signaling at the level of the brainstem stimulates colonic secretory-motor function through activation of colonic enteric neurons.