Thickness of the bone-cartilage unit in relation to osteoarthritis severity in the human hip joint.
Louise Brøndt HartlevRasmus Klose-JensenJesper Skovhus ThomsenJens Randel NyengaardLene Warner Thorup BoelMogens Berg LaursenTrine Bay LaurbergAndreas Wiggers NielsenKristian Steengaard-PedersenEllen-Margrethe HaugePublished in: RMD open (2018)
The study showed that thicker CC is present in early stages of OA, suggesting that bone formation by endochondral ossification is an early phenomenon of OA. Thickening of the SCB was present, but only in areas with denuded bone. Suggesting that also appositional bone growth occurs and that it may be a consequence of changed biomechanics.