Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data.

Michelle Ying Ya LeeKlaus H KaestnerMingyao Li

Published in: Genome biology (2023)

Seurat v4 is the best currently available platform for integrating scRNA-seq, snATAC-seq, and multiome data even in the presence of complex batch effects.

Keyphrases

rna seq
single cell
high throughput
electronic health record
big data
machine learning
artificial intelligence
dna methylation