Body Mass Index and Uterine Fibroid Development: A Prospective Study.

Quaker E HarmonStacy PatchelSheri DenslowGanesa WegienkaDonna D Baird

Published in: The Journal of clinical endocrinology and metabolism (2024)

BMI has a non-linear association with fibroid incidence that could be driven by effects of BMI on inflammation and reproductive hormones. More detailed measures of visceral and subcutaneous adiposity and their effects on hormones, DNA damage, and cell death are needed.

Keyphrases

dna damage
cell death
oxidative stress
weight gain
body mass index
insulin resistance
risk factors
dna repair
metabolic syndrome
type diabetes
adipose tissue
cell proliferation