A novel two-step administration of XPO-1 inhibitor may enhance the effect of anti-BCMA CAR-T in relapsed/refractory extramedullary multiple myeloma.
Di WangHaiying FuYimei QueHaitao RuanMenglei XuXiaolu LongQiuxia YuChunhui LiZhe LiSongbai CaiWei ChenCong SunGuang HuShuai WangDonggou HeJianming MeiWen WangChun-Rui LiPublished in: Journal of translational medicine (2023)
The combination of Selinexor and CT103A exerts preliminary synergistic effect, and can be developed as a promising strategy for relapsed/refractory extramedullary myeloma.