The impact of EGFR T790M mutation status following the development of Osimertinib resistance on the efficacy of Osimertinib in non-small cell lung cancer: A meta-analysis.
Liuxian GuoGuojin ZhouMin HuangKejing TangJing XuJie ChenPublished in: The clinical respiratory journal (2024)
Persistence of the T790M gene mutation after the development of Osimertinib resistance is associated with higher therapeutic benefits of Osimertinib in NSCLC patients. The results of tissue detection are more significant than those of plasma detection.
Keyphrases
- small cell lung cancer
- advanced non small cell lung cancer
- epidermal growth factor receptor
- end stage renal disease
- brain metastases
- tyrosine kinase
- newly diagnosed
- ejection fraction
- chronic kidney disease
- loop mediated isothermal amplification
- prognostic factors
- real time pcr
- label free
- patient reported outcomes