Severity of in vivo corticospinal tract degeneration is associated with survival in amyotrophic lateral sclerosis: a longitudinal, multicohort study.

Daniel TaAbdullah H IshaqueAdam ElamyTanushka AnandAndrew WuDean T EurichCollin LukYee Hong YangSanjay Kalra

Published in: European journal of neurology (2023)

Severity of cerebral degeneration is associated with survival in ALS. CST degeneration progresses faster in subgroups of patients with shorter survival. Neuroimaging holds promise as a tool to improve patient management and facilitation of clinical trials.

Keyphrases

clinical trial
free survival
big data
brain injury
deep learning
study protocol
amyotrophic lateral sclerosis