Atrial cardiomyocytes contribute to the inflammatory status associated with atrial fibrillation in right heart disease.
Ewen Le QuilliecCharles-Alexandre LeBlancOrlane NeuillyJiening XiaoRim YounesYasemin AltuntasFeng XiongPatrice NaudLouis VilleneuveMartin G SiroisJean-François TanguayJean Claude TardifRoddy HiramPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
Right heart disease-induced arrhythmogenicity may occur due to dysfunctional SERCA2a and inflammatory signalling generated from injured RA CM, which leads to an increased risk of AF.
Keyphrases
- atrial fibrillation
- high glucose
- catheter ablation
- left atrial
- pulmonary hypertension
- oxidative stress
- oral anticoagulants
- left atrial appendage
- direct oral anticoagulants
- diabetic rats
- rheumatoid arthritis
- heart failure
- percutaneous coronary intervention
- endothelial cells
- coronary artery disease
- disease activity
- acute coronary syndrome
- systemic lupus erythematosus