Pharmacokinetics of isoniazid in children with tuberculosis-A comparative study at two doses.
Ira ShahSajal Kumar DasNaman S ShettyT KannanGeetha RamachandranAk Hemanth KumarPublished in: Pediatric pulmonology (2020)
Children on daily INH 10 mg/kg/day have higher AUC and Cmax than the required therapeutic range whereas over 65% of children with daily 5 mg/kg/day INH therapy failed to achieve the optimal therapeutic range.