Association of Angiotensin II Receptor Type 1 and Endothelin-1 Receptor Type A Agonistic Autoantibodies With Adverse Remodeling and Cardiovascular Events After Acute Myocardial Infarction.
Francesco TonaGiovanni CivieriMarta VadoriGiulia MasieroLaura IopMartina Perazzolo MarraValentina PerinElisa CucizAnnagrazia CecereGiacomo BernavaDonatella TansellaNataliia NaumovaSimran GrewalEmanuele CozziSabino IlicetoPublished in: Journal of the American Heart Association (2024)
AT1R-AAs and ETAR-AAs are associated with LVR in patients with ST-segment-elevation myocardial infarction. AT1R-AAs are also significantly associated with recurrent major adverse cardiac events. These initial observations may set the stage for a better pathophysiological understanding of the mechanisms contributing to LVR and ST-segment-elevation myocardial infarction prognosis.
Keyphrases
- st segment elevation myocardial infarction
- percutaneous coronary intervention
- cardiovascular events
- angiotensin ii
- acute myocardial infarction
- coronary artery disease
- acute coronary syndrome
- angiotensin converting enzyme
- vascular smooth muscle cells
- left ventricular
- cardiovascular disease
- systemic lupus erythematosus
- atrial fibrillation
- type diabetes
- adverse drug
- emergency department
- binding protein