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Lymphatic mapping for image-guided radiotherapy in patients with locally advanced uterine cervical cancer: a feasibility study.

Judit A AdamEdwin PoelBerthe L F van Eck-SmitConstantijne H MomLukas J A StalpersJaap StokerShandra Bipat
Published in: EJNMMI research (2023)
Lymphatic mapping is feasible in LACC. Almost 60% of nodes at risk received suboptimal treatment during chemoradiation. As treatment failure could be caused by (micro)metastasis in some of these nodes, including nodes at risk in the radiotherapy treatment volume could improve radiotherapy treatment outcome in LACC. Trail registration The study was first registered at the International Clinical Trial Registry Platform (ICTRP) under number of NL9323 on 4 March 2021. Considering the source platform was not operational anymore, the study was retrospectively registered again on February 27, 2023 at CilicalTrials.gov under number of NCT05746156.
Keyphrases
  • locally advanced
  • clinical trial
  • rectal cancer
  • early stage
  • squamous cell carcinoma
  • lymph node
  • high throughput
  • neoadjuvant chemotherapy
  • radiation induced
  • study protocol
  • open label
  • mass spectrometry