A Passive Membrane System for On-line Mass Spectrometry Reagent Addition.
Taelor M ZarkovicScott A BordenErik T KroghChris G GillPublished in: Rapid communications in mass spectrometry : RCM (2023)
An on-line mass spectrometry ionization reagent addition method with potential post-chromatography reagent addition applications was developed using a hollow fibre polydimethylsiloxane membrane. This approach offers a promising alternative to traditional methods requiring additional hardware such as pumps and T-junctions that can result in sample dilution and imperfect reagent mixing.