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Targeting Glypican-1 Reverses Resistance to 5-Fluorouracil in Esophageal Adenocarcinoma Cells.

Akshay PratapAndrea QualmanHedlund GarrettErlinda TheArgudit ChauhanJuan P IdrovoLinling ChengSachin WaniRobert Alexander MeguidXianzhong Meng
Published in: Anticancer research (2023)
Silencing GPC-1 has the potential to augment the efficacy of 5-FU chemotherapy in resistant EAC tumors.
Keyphrases
  • induced apoptosis
  • locally advanced
  • cell cycle arrest
  • squamous cell carcinoma
  • oxidative stress
  • radiation therapy
  • rectal cancer