Daily salivary cortisol and cortisone rhythm in patients with adrenal incidentaloma.
Filippo CeccatoMattia BarbotNora AlbigerGiorgia AntonelliMarialuisa ZilioMarco TodeschiniDaniela RegazzoMario PlebaniCarmelo LacognataMaurizio IacoboneFranco ManteroMarco BoscaroCarla ScaroniPublished in: Endocrine (2017)
Daily cortisol exposure, evaluated with AUC from multiple saliva collections, is increased in AI patients with serum cortisol > 50 nmol/L after DST, especially in the morning, leading to reduced corticotropin levels. Cortisol rhythm is preserved in patients with AI, remarking that LNSC is not a screening test for subclinical hypercortisolism.