Identification of Urinary Biomarkers for Exercise-Induced Immunosuppression by iTRAQ Proteomics.

Guoqin XuWentao LinAndrew J McAinchXu YanXiquan Weng

Published in: BioMed research international (2020)

Four weeks of incremental treadmill running induced immunosuppression in healthy males. By using iTRAQ proteomics, four proteins in the urine, SEMG-1, PIP, PDGFRL, and NDPK, were found to increase incrementally with the increased exercise intensity, which have the potential to be used as noninvasive immune biomarkers of exercise-induced immunosuppression.

Keyphrases

high intensity
mass spectrometry
high glucose
diabetic rats
resistance training
drug induced
oxidative stress
endothelial cells
human health