Humoral immune response to SARS-CoV-2 mRNA vaccines is associated with choice of vaccine and systemic adverse reactions.

Hanna Klingel Alexander Krüttgen Matthias Imöhl Michael Kleines

Published in: Clinical and experimental vaccine research (2023)

Further investigations should focus on the possible advantages of homologous and heterologous booster vaccinations and their capability of stimulating memory B-cells. Additionally, understanding inflammatory processes induced by mRNA vaccines might help to improve reactogenicity while maintaining immunogenicity and efficacy.

Keyphrases

immune response
sars cov
binding protein
dendritic cells
dna damage
respiratory syndrome coronavirus
oxidative stress
toll like receptor
dna repair
working memory
emergency department
adverse drug
inflammatory response
drug induced
electronic health record