Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.

Michelle van GeldermalsenLake-Ee QuekNigel TurnerNatasha FreidmanAngel PangYi Fang GuanJames R KrycerRenae RyanQian WangJeff Holst

Published in: BMC cancer (2018)

Together these data showed that BenSer blockade inhibited breast cancer cell growth and viability through disruption of intracellular amino acid homeostasis and inhibition of downstream metabolic and growth pathways.

Keyphrases

amino acid
reactive oxygen species
electronic health record
big data
young adults
artificial intelligence
childhood cancer