A Multicenter Analysis of Immune Checkpoint Inhibitors as Adjuvant Therapy Following Treatment of Isolated Brain Metastasis.

James Randall PatrinleyElisa Funck-BrentanoKhang NguyenSuthee RapisuwonJoe-Elie SalemGeoffrey T GibneyMatteo CarlinoDouglas B Johnson

Published in: The oncologist (2020)

Patients with isolated brain metastases treated with surgery or SRS appeared to benefit from adjuvant ICI therapy, particularly with combination therapy. Recurrences in this setting appear to largely occur intracranially.

Keyphrases

combination therapy
brain metastases
small cell lung cancer
minimally invasive
early stage
coronary artery bypass
white matter
clinical trial
stem cells
surgical site infection
double blind
acute coronary syndrome
subarachnoid hemorrhage
smoking cessation