A polygenic risk score predicts atrial fibrillation in cardiovascular disease.

Nicholas A MarstonAmanda C GarfinkelFrederick K KamanuGiorgio M MelloniCarolina Roselli Petr JarolímDavid D BergDeepak L BhattMarc P BonacaChristopher P CannonRobert P GiuglianoMichelle L O'DonoghueItamar RazBenjamin M SciricaEugene BraunwaldDavid A MorrowPatrick T Ellinor Steven A LubitzMarc S SabatineChristian T Ruff

Published in: European heart journal (2022)

In patients with cardiovascular conditions, AF PRS is a strong independent predictor of incident AF that provides complementary predictive value when added to a validated clinical risk score and NT-proBNP.

Keyphrases

atrial fibrillation
cardiovascular disease
oral anticoagulants
catheter ablation
left atrial
left atrial appendage
direct oral anticoagulants
heart failure
type diabetes
percutaneous coronary intervention
cardiovascular events
cardiovascular risk factors
metabolic syndrome
mitral valve