Sex Differences in the Association between Inflammation and Ischemic Heart Disease.
Michael FiechterAhmed HaiderSusan BengsMonika MarȩdziakIrene A BurgerAndrea RoggoAngela PortmannGeoffrey I WarnockKatharina SchadeValerie TreyerAnton S BeckerMichael MesserliElia von FeltenDominik C BenzTobias A FuchsChristoph GräniAju P PazhenkottilRonny R BuechelPhilipp A KaufmannCatherine GebhardPublished in: Thrombosis and haemostasis (2019)
A strong link between bone marrow metabolism and impaired myocardial function and perfusion was observed in women, but not in men. Our data suggest that novel biomarkers of inflammation might help to identify women at risk for ischemic cardiomyopathy and to tailor disease management to the female cardiovascular phenotype.
Keyphrases
- bone marrow
- polycystic ovary syndrome
- oxidative stress
- pregnancy outcomes
- mesenchymal stem cells
- cervical cancer screening
- heart failure
- left ventricular
- electronic health record
- breast cancer risk
- ischemia reperfusion injury
- type diabetes
- metabolic syndrome
- magnetic resonance imaging
- big data
- magnetic resonance
- computed tomography
- adipose tissue
- machine learning
- artificial intelligence
- data analysis
- skeletal muscle