Humanin gene expression in subjects with Parkinson's disease.

Michele SalemiFederico RidolfoMaria Grazia SalluzzoFrancesca A SchillaciSalvatore CanigliaBartolo LanuzzaMariagiovanna CantoneRaffaele Ferri

Published in: Molecular biology reports (2023)

In conclusion, the present data confirm the tendency of mitochondria to overexpress mRNA in PD, which could be a cellular attempt to reduce apoptotic damage in PD subjects. Humanin might be useful as a marker for a better diagnosis of PD, and we cannot exclude that in the future it might also play a role on prognosis and in the possible therapies for PD.

Keyphrases

gene expression
cell death
dna methylation
oxidative stress
electronic health record
machine learning
big data
artificial intelligence
reactive oxygen species
deep learning