Exercise-dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF-SRF signalling.

Francesca SolagnaLeonardo NogaraKenneth A DyarFranziska GreulichAshfaq A MirClara TürkTheresa BockAlessia GeremiaMartina BaraldoRoberta SartoriJean FarupHenriette UhlenhautKristian VissingMarcus KrügerBert Blaauw

Published in: Acta physiologica (Oxford, England) (2020)

Our results identify a new exercise signalling fingerprint in vivo, instrumental for exercise-induced protein synthesis and potentially muscle growth.

Keyphrases

high intensity
physical activity
resistance training
gene expression
dna damage
skeletal muscle
transcription factor
quality control