Role of metronomic therapy for advanced oral cancers and predictors of response: A multi-institutional feasibility study.

Mahesh SultaniaMohammed ImaduddinSuryanarayana S V DeoMadhabananda KarDillip K MudulySunil KumarAtul SharmaAshutosh MishraSaroj K D MajumdarAmit K AdhyaDilip K Parida

Published in: Head & neck (2021)

Constraint-adapted approach of using methotrexate and celecoxib is economical with good compliance, minimal toxicity, and good efficacy. It is feasible for use in diverse settings. Individualized selection of patients based on response predictors may maximize metronomic therapy's benefit.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
prognostic factors
oxidative stress
stem cells
low dose
young adults
bone marrow
patient reported
oxide nanoparticles