Combination of DNA methylation biomarkers with multiparametric magnetic resonance and ultrasound imaging fusion biopsy to detect the local spread of prostate cancer.
Augustinas MatulevičiusKristina ŽukauskaitėRugilė GineikaitėDarius DasevičiusMantas TrakymasIeva NaruševičiūtėJurgita UšinskienėAlbertas UlysFeliksas JankevičiusSonata JarmalaitėPublished in: The Prostate (2023)
Thus, this study suggests that for focal therapy by region target hemi-ablation, the safe distance from the index lesion is no less than 10 mm. Noninvasive urine DNA methylation tests in combination with PSAD could be used for further follow-up of the patients, but larger prospective studies with external validation are needed.
Keyphrases
- dna methylation
- prostate cancer
- magnetic resonance
- end stage renal disease
- gene expression
- ejection fraction
- genome wide
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- radical prostatectomy
- stem cells
- mesenchymal stem cells
- patient reported outcomes
- atrial fibrillation
- bone marrow
- contrast enhanced
- cell therapy
- case control
- patient reported