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Accuracy, robustness and scalability of dimensionality reduction methods for single-cell RNA-seq analysis.

Shiquan SunJiaqiang ZhuYing MaXiang Zhou
Published in: Genome biology (2019)
Based on the comprehensive evaluation results, we provide important guidelines for choosing dimensionality reduction methods for scRNA-seq data analysis. We also provide all analysis scripts used in the present study at www.xzlab.org/reproduce.html.
Keyphrases
  • rna seq
  • single cell
  • data analysis
  • high throughput
  • genome wide
  • gene expression
  • clinical practice