Exploring the Role of Antithrombin in Nephrotic Syndrome-Associated Hypercoagulopathy: A Multi-Cohort Study and Meta-Analysis.
Eman AbdelghaniAmanda P WallerKatelyn J WolfgangJoseph R StanekSamir V ParikhBrad H RovinWilliam E SmoyerBryce A Kerlinnull nullnull nullPublished in: Clinical journal of the American Society of Nephrology : CJASN (2023)
These data suggest that AT deficiency plays only a limited role in the mechanisms underlying the acquired hypercoagulopathy of nephrotic syndrome. Moreover, AT deficiency was not present in all patients with nephrotic syndrome and was more likely in children than adults despite the higher risk for venous thromboembolism in adults than children.