Synthesis of 1-Azaanthraquinone: Sequential C-N Bond Formation/Lewis Acid Catalyzed Intramolecular Cyclization Strategy.

A synthetic strategy has been developed for the synthesis of 1-azaanthraquinones. This synthetic protocol consists of sequential Pd-catalyzed carbon-nitrogen bond formation followed by Lewis acid catalyzed intramolecular cyclization. The Pd-catalyzed aminated intermediate was isolated and characterized. This sequential reactions strategy provides a wide range of 1-azaanthraquinones with good yields.