Soluble HLA peptidome of pleural effusions is a valuable source for tumor antigens.
Sofia Khazan-KostGal CafriDganit Melamed KadoshNavit MooshayefSumit ChatterjiDan DominissiniSigal ManorBracha ZisserLimor BrodayEfrosiniia TalalaiAnat ShemerOranit ZadokEfrat OfekAmir OnnArie AdmonMichael PeledPublished in: Journal for immunotherapy of cancer (2022)
Pleural effusions contain sHLA-peptide complexes, and the pleural effusion HLA peptidome of patients with malignant tumors can serve as a rich source of biomarkers for tumor diagnosis and potential candidates for personalized immunotherapy.
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