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Transendothelial Insulin Transport is Impaired in Skeletal Muscle Capillaries of Obese Male Mice.

Ian M WilliamsP Mason McClatcheyDeanna P BracyJeffrey S BonnerFrancisco A ValenzuelaDavid H Wasserman
Published in: Obesity (Silver Spring, Md.) (2020)
These results suggest that, in male mice, obesity results in ultrastructural alterations to the capillary endothelium that delay EIT. Nonetheless, the myocyte appears to exceed the endothelium as a contributor to SkM IR in DIO male mice.
Keyphrases
  • type diabetes
  • skeletal muscle
  • insulin resistance
  • weight loss
  • metabolic syndrome
  • nitric oxide
  • adipose tissue
  • glycemic control
  • bariatric surgery
  • high fat diet induced
  • weight gain
  • body mass index