Interaction of environmental factors with the polygenic risk scores of thinness-related genes in preventing obesity risk in middle-aged adults: The KoGES.
Jun-Yu ZhouMeiling LiuSun-Min ParkPublished in: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association (2023)
In conclusion, adults having a high-PRS were significantly correlated with being underweight, especially in combination with a particular nutritional status. These results show the potential for thinness genes to be applied to personalised nutrition for preventing obesity through targeted gene therapy.