A proposed HLA-B*27 screening method for ankylosing spondylitis detection based on tag-single nucleotide polymorphisms: a preliminary study.
Gabriela Angélica Martínez-NavaYessica Zamudio-CuevasNinoska Aleida Terrazas-OntiverosKarina Martínez FloresRolando Espinosa-MoralesFernando Mijares-DíazShaila Monserrat Juárez-BarretoCarlos Alberto LozadaMargarita Valdés-FloresRoberto Sánchez-SánchezAlberto Hidalgo-BravoJavier Fernández-TorresPublished in: Molecular biology reports (2021)
HLA-B*27 tag-SNPs are associated with AS susceptibility; furthermore, the rs4349859 SNP by its own have an outstanding performance in detecting HLA-B*27 and therefore can be proposed as screening marker in the identification of HLA-B*27 in our population.