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EARLY gestational exposure to isoflurane causes persistent cell loss in the dentate gyrus of adult male rats.

Arvind PalanisamyGregory CrosbyDeborah J Culley
Published in: Behavioral and brain functions : BBF (2017)
Our results show that maternal isoflurane anesthesia in rodents causes region-specific cell loss in the hippocampus of adult male offspring. These changes may, in part, account for the behavioral deficits reported in adult rats exposed to isoflurane in utero.
Keyphrases
  • single cell
  • cell therapy
  • pregnant women
  • traumatic brain injury
  • birth weight
  • weight gain
  • childhood cancer
  • high fat diet
  • type diabetes
  • metabolic syndrome
  • young adults
  • skeletal muscle
  • brain injury