Antimicrobial therapy and outcome of methicillin-resistant Staphylococcus aureus endocarditis: A retrospective multicenter study in Japan.
Kotaro MitsutakeNatsuki ShinyaMasafumi SekiTakahiro OharaKohei UemuraMasato FukunagaJun SakaiMiki NagaoMakoto SataYohei HamadaHitoshi KawasujiYoshihiro YamamotoMasashi NakamatsuYusuke KoizumiHiroshige MikamoAkira UkimuraTetsuji AoyagiToyomitsu SawaiTakeshi TanakaKoichi IzumikawaYoko TakayamaKiwamu NakamuraKeiji KanemitsuIssei TokimatsuKazuhiko NakajimaDai AkinePublished in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (2024)
Glycopeptide and daptomycin were the preferred antibiotics for the initial therapy of MRSA-IE. Antimicrobial regimens were changed for various reasons. Prognosis was not significantly affected by choice of antibiotic therapy (glycopeptide, daptomycin, linezolid), but further studies are needed to determine which antimicrobials are optimal as first-line agents.