HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer.

Tony C Y PangZhihong XuAlpha Raj MekapoguSrinivasa P Pothula Therese Maria BeckerSusan CorleyMarc R WilkinsDavid GoldsteinRomano PirolaJeremy WilsonMinoti Apte

Published in: Cancers (2021)

This study is the first to demonstrate the efficacy of adjuvant HGF/c-Met inhibition for PC and provides the first confirmation of the existence of circulating PSCs.

Keyphrases

mouse model
tyrosine kinase
weight loss
glycemic control