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Eighteen-Month Real-World Experience Using Mavacamten for Treatment of Obstructive Hypertrophic Cardiomyopathy in a Racially Diverse Population.

Diego RamonfaurAlessio GasperettiVictoria E BlakeBryana RiversAli A KassamaliEdward K KasperLili A BarouchKatherine C WuJose A MadrazoRichard T Carrick
Published in: Journal of the American Heart Association (2024)
Mavacamten was effective and safe when used under real-world conditions in a racially diverse population of symptomatic patients with obstructive hypertrophic cardiomyopathy. Patients with comorbid obesity were less likely to experience symptomatic improvement while on mavacamten.
Keyphrases
  • hypertrophic cardiomyopathy
  • left ventricular
  • metabolic syndrome
  • type diabetes
  • insulin resistance
  • weight loss
  • weight gain
  • adipose tissue
  • body mass index
  • skeletal muscle
  • physical activity
  • smoking cessation