Prediction of Free Drug Absorption in Cyclodextrin Formulation by a Modified Physiologically Based Pharmacokinetic Model and Phase Solubility 3-D Surface Graph.

Published in: Pharmaceutical research (2021)

This PBPK model and 3-D surface graph can predict the absorption and determine the optimal concentration ratio of CD formulation, which could accelerate the R&D of CD formulation.

Keyphrases

drug delivery
convolutional neural network
emergency department
neural network
mass spectrometry
deep learning
capillary electrophoresis