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MondoA and AKI and AKI-to-CKD Transition.

Shihomi MaedaShinsuke SakaiYoshitsugu TakabatakeTakeshi YamamotoSatoshi MinamiJun NakamuraTomoko Namba-HamanoAtsushi TakahashiJun MatsudaHiroaki YonishiSho MatsuiAtsuhiro ImaiRyuya EdahiroHitomi Yamamoto-ImotoIsao MatsuiSeiji TakashimaRyoichi ImamuraNorio NonomuraMotoko YanagitaYukinori OkadaAndrea BalabioShuhei NakamuraTamotsu YoshimoriYoshitaka Isaka
Published in: Journal of the American Society of Nephrology : JASN (2024)
Our findings demonstrate that MondoA protected against vulnerability to AKI by maintaining autophagy and subsequently supporting mitochondrial function to prevent progression to CKD.
Keyphrases
  • acute kidney injury
  • chronic kidney disease
  • cell death
  • climate change
  • signaling pathway
  • endoplasmic reticulum stress
  • oxidative stress