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Model of disease severity in alcoholic hepatitis and novel prognostic insights.

Vlad-Teodor EnciuPriscila Mădălina OlogeanuAna-Maria Călin-NeculaAlexandru Constantin MoldoveanuGabriela Oprea-CălinCarmen Fierbinţeanu-Braticevici
Published in: Romanian journal of internal medicine = Revue roumaine de medecine interne (2024)
We obtained a new prognostic score for the assessment of 30-day mortality in AH that includes markers of inflammation (CRP, fever) and markers of sarcopenia (CHI) along parameters of hepatic disfunction (total bilirubin and PT). Amongst consecrated prognostic models, MDF and Lille scores were representative for our study, while ABIC, GAHS and MELD-Na did not attain statistical significance. Our score is unique by the addition of CRP and this could prove to be a useful tool in AH severity stratification.
Keyphrases
  • oxidative stress
  • skeletal muscle
  • risk factors
  • type diabetes
  • liver injury
  • coronary artery disease
  • community dwelling