Synthesis of carbon-11 radiolabelled transition metal complexes using 11 C-dithiocarbamates.
Sara CesarecFraser EdgarTitan LaiChristophe PlissonAndrew J P WhitePhilip W MillerPublished in: Dalton transactions (Cambridge, England : 2003) (2022)
A novel radiolabelling method exploiting 11 C-dithiocarbamate ligands has been used to generate 11 C-labelled Au(I), Au(III), Pd(II) and Pt(II) complexes in high radiochemical yields (71-99%). Labelled complexes were prepared in a rapid one-pot procedure via the substitution reaction of 11 C-dithiocarbamate ligands with appropriate transition metal chloride precursors.