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Association of frequent NF2 mutations with spinal location predominance and worse outcomes in psammomatous meningiomas.

Leihao RenQing XieJiaojiao DengJiawei ChenJinxiu YuDaijun WangHiroaki WakimotoYe GongLingyang Hua
Published in: Journal of neurosurgery (2024)
Female sex and spinal location predominance were statistically significant in PMs. NF2 mutation was an independent predictor for worse PFS of PMs. Of note, NF2 mutation was detected in all SPMs but in only 38.46% of CPMs, revealing a significant difference.
Keyphrases
  • signaling pathway
  • lps induced
  • pi k akt
  • nuclear factor
  • spinal cord
  • oxidative stress
  • type diabetes
  • metabolic syndrome
  • toll like receptor
  • immune response
  • cell proliferation
  • weight loss
  • glycemic control