Asymmetric Synthesis of Axinellamines A and B.

Zhiqiang MaXiao WangYuyong MaChuo Chen

Published in: Angewandte Chemie (International ed. in English) (2016)

Axinellamines A and B are broad-spectrum antibacterial pyrrole-imidazole alkaloids that have a complex polycyclic skeleton. A new asymmetric synthesis of these marine sponge metabolites is described herein, featuring an oxidative rearrangement and an anchimeric chlorination reaction.

Keyphrases

drinking water
ms ms
solid state