Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker.
Tilo WinklerPuja KohliVanessa J KellyEkaterina G KehlAlison S WitkinJosanna M Rodriguez-LopezKathryn A HibbertMamary T KoneDavid M SystromAaron B WaxmanJose G VenegasRichard N ChannickR Scott HarrisPublished in: Respiratory research (2022)
Perfusion imaging during O2 + iNO showed a significant difference in the heterogeneity associated with the vertical gradient in perfusion, distinguishing in this small cohort study PAH subjects from controls.