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Network Pharmacology and Experimental Validation to Explore the Effect and Mechanism of Kanglaite Injection Against Triple-Negative Breast Cancer.
Mei Zhao
Lijuan Fu
Panling Xu
Ting Wang
Ping Li
Published in:
Drug design, development and therapy (2023)
By utilizing network pharmacology, molecular docking, and in vitro experiments, KLTi was confirmed to have anti-TNBC effects by arresting cell cycle and inhibiting CDK1 dephosphorylation.
Keyphrases
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cell cycle
molecular docking
cell proliferation
molecular dynamics simulations
signaling pathway
ultrasound guided
network analysis