Serum glial fibrillary acidic protein indicates memory impairment in patients with chronic heart failure.
Jan TraubMarkus OttoRoxane SellGyörgy A HomolaPetra SteinackerPatrick OecklCaroline MorbachStefan FrantzMirko PhamStefan StörkGuido StollAnna FreyPublished in: ESC heart failure (2022)
Serum GFAP levels are affected by age, smoking, and surrogates of the severity of HF. The association of GFAP with memory dysfunction suggests that astroglial pathologies, which evade detection by conventional MRI, may contribute to memory loss beyond ageing in patients with chronic HF.