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LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy.

Stanislav A VasilyevEkaterina N TolmachevaOksana Yu VasilyevaAnton V MarkovDaria I ZhigalinaLada A ZatulaVasilissa A LeeEkaterina S SerdyukovaElena A SazhenovaTatiana V NikitinaEkaterina N TolmachevaIgor N Lebedev
Published in: Journal of assisted reproduction and genetics (2020)
Our results indicate that the pathogenic effects of aneuploidy in human embryogenesis can be supplemented with significant epigenetic changes in the repetitive sequences.
Keyphrases
  • dna methylation
  • endothelial cells
  • gene expression
  • high frequency
  • induced pluripotent stem cells
  • genome wide
  • genetic diversity
  • genome wide identification