SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I.

Longjie SunZheng LvXuexue ChenChaofan WangPengbo LvLu YanShuang TianXiaomei XieXiaohong YaoJingjing LiuZhao WangHaoshu LuoSheng CuiJiali Liu

Published in: BMC biology (2023)

Altogether, our data reveal the critical role of an SRSF1-mediated posttranscriptional regulatory mechanism in the mouse oocyte meiotic prophase I program, providing a framework to elucidate the molecular mechanisms of the posttranscriptional network underlying primordial follicle formation.

Keyphrases

germ cell
quality improvement
electronic health record
transcription factor
single cell
molecularly imprinted
machine learning
high resolution
data analysis
network analysis