Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.

Leena GeorgeAdam R TaylorAnna Esteve-CodinaMaría Soler ArtigasGian Andri ThunStewart BatesStelios PavlidisScott WagersAnne BolandAntje PrassePiera BoschettoDavid G ParrAdam NowinskiImre BartaJens HohlfeldTimm GreulichMaarten van den BergePieter S HiemstraWim TimensTimothy HinksSally WenzelSalman SiddiquiMatthew RichardsonPer VengeSimon HeathIvo GutMartin D TobinLindsay EdwardsJohn H RileyRatko DjukanovicCharles AuffrayBertrand De-MeulderSven Erik-DahlenIan M AdcockKian Fan ChungLoems Ziegler-HeitbrockPeter J SterkDave SinghChristopher E Brightlingnull null

Published in: Allergy (2019)

Despite shared "treatable traits" between asthma and COPD, the molecular mechanisms underlying these clinical entities are predominately different.

Keyphrases

chronic obstructive pulmonary disease
lung function
cystic fibrosis
genome wide
air pollution
single cell
rna seq
peripheral blood
dna methylation